On the basis of the National 863 Key Project "Development of Nano-biosensor for Early Diagnosis of Tumors" and the support of the novel coronavirus emergency research project of Guangxi Science and Technology Department, the team takes novel coronavirus as the research object.A series of detection reagents (including novel Coronavirus antigen detection kit, novel Coronavirus IgM/IgG antibody detection kit and novel Coronavirus neutralizing antibody detection kit) have been developed for rapid, economic, high sensitivity, high selectivity, simple operation and practical application for Coronavirus specific early screening and prognosis vaccine evaluation.The product has been incubated and industrialized, and has passed clinical trials. Its accuracy, repeatability and other key technical indicators are in the leading level among similar products at home and abroad.